The ClinGen SVCv4 Pilot Calculator is intended for use in piloting the DRAFT ACMG/AMP/CAP/ClinGen Standards for Sequence Variant Classification v4.0 framework. It is not intended for clinical use.

Please provide your feedback on the SVCv4 framework through the appropriate Feedback Form available in the Feedback section of the Main Navigation Menu.

Detailed guidance for using each of the code-specific workflows and additional resources for the Pilot are available in the Guidance section of the Main Navigation Menu.

For questions related to the use of the SVCv4 framework or questions about the Pilot process please contact us through SVCv4 Pilot help desk Email

Should you encounter any issues regarding the data displayed, or other problems with the calculator tool, please let us know through the Software Help Desk